Rat Anti-Mouse CD45-FITC
Cat# 1660-02S
Size : 0.1mg
Brand : Southern Biotech
Contact local distributor :
Phone : +1 850 650 7790
| Clone | I3/2.3 |
|---|---|
| Isotype | Rat (Lewis) IgG2bλ |
| Isotype Control | Rat IgG2b-FITC (KLH/G2b-1-2) |
| Specificity | Mouse CD45 |
| Alternative Names | LCA, leukocyte common antigen, T200, Ly-5, Receptor-type tyrosine-protein phosphatase C, Lyt-4, Ptprc |
| Description | CD45 is the common leukocyte antigen and is expressed on all cells of hematopoietic origin except erythrocytes. CD45 exists as a number of different isoforms which result from alternative RNA splicing of exons 4, 5 and 6. The I3/2.3 monoclonal antibody recognizes a framework epitope present on all CD45 isoforms. The CD45 molecule has been implicated as playing a key role in thymic development and in antigen-driven proliferation of T cells. |
| Immunogen | T1M1 (Thy-1;Formulation"> Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.1 mg/mL, 0.5 mg/mL |
| Volume | 1.0 mL |
| Recommended Storage | 2-8,5-7 Immunohistochemistry-Frozen Sections ,4 Immunoprecipitation ,2 |
| RRID Number | AB_2795098 |
| Gene ID | 19264 (Mouse) |
| Gene ID Symbol | Ptprc (Mouse) |
| Gene ID Aliases | loc; B220; Cd45; L-CA; Ly-5; T200; CD45R; Lyt-4 |
| UniProt ID | P06800 (Mouse |
| UniProt Name | PTPRC_MOUSE (Mouse) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 2. Haidl ID, Ng DH, Rothenberger S, Johnson P, Jefferies WA. Detection of restricted isoform expression and tyrosine phosphatase activity of CD45 in murine dendritic cells. Eur J Immunol. 1995;25:3370-4. (FC, IP)
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- 4. Villalta SA, Lang J, Kubeck S, Kabre B, Szot GL, Calderon B, et al. Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet function. Diabetes. 2013;62:2870-8. (IHC-FS)
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- 6. Matsunaga H, Hokari R, Kurihara C, Okada Y, Takebayashi K, Okudaira K, et al. Omega-3 fatty acids exacerbate DSS-induced colitis through decreased adiponectin in colonic subepithelial myofibroblasts. Inflamm Bowel Dis. 2008;14:1348-57. (FC)
- 7. Domingos-Pereira S, Decrausaz L, Derré L, Bobst M, Romero P, Schiller JT, et al. Intravaginal TLR agonists increase local vaccine-specific CD8 T cells and human papillomavirus-associated genital-tumor regression in mice. Mucosal Immunol. 2013;6:393-404. (FC)
