Reagents and instruments for immunology, cell biology and molecular biology.
 
> STM2457 [2499663-01-1]

STM2457 [2499663-01-1]

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Cat# HY-134836-5mg

Size : 5mg

Brand : MedChemExpress

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Based on 39 publication(s) in Google Scholar

Description

STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC50 of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML)[1][2].

In Vitro

STM2457 (Compound 72) inhibits MOLM13 cells proliferation with an IC50 of 8.699 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

STM2457 Related Antibodies

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (112.48 mM; ultrasonic and warming and heat to 60;">

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2496 mL 11.2478 mL 22.4957 mL
5 mM 0.4499 mL 2.2496 mL 4.4991 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80 months; -20 month. When stored at -80 months. When stored at -20 month.

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