Quimigen Portugal > TENASCIN Antibody
TENASCIN Antibody
Brand : Aviva Systems Biology
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Datasheets/Manuals | Printable datasheet for TENASCIN Antibody (OAAD00204) - OAAD00204 |
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Predicted Species Reactivity | Human |
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Clonality | Monoclonal |
Clone | T20 |
Isotype | IgG1 |
Host | Mouse |
Application | IF, IHC |
Reconstitution and Storage | At -20C for one year. After reconstitution, at 4C for three month. It can also be aliquotted and stored frozen at -20C for longer time. |
Immunogen | Human tenascin. |
Purification | Purified by the goat anti-mouse IgG Affinity chromatography. |
Specificity | Human. No cross reactivity with other proteins. |
Formulation | Lyophilized from 1.2% sodium acetate, with 2mg BSA and 0.01mg NaN3 as preservative. |
Application Info | Western blot At 1-2ug/ml with the appropriate system to detect tenascin in cells and tissues. Immunohistochemistry(P) At 2-4ug/ml to detect tenascin in formalin fixed and paraffin embedded tissues. Immunohistochemistry(F) At 2-4ug/ml to detect tenascin in formalin or acetone fixed tissues. Immunocytochemistry Suitable Other applications have not been tested. Optimal dilutions should be determined by end user. |
Storage Buffer | 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml. |
Reference | 1. Saga, Y.; Yagi, T.; Ikawa, Y.; Sakakura, T.; Aizawa, S. : Mice develop normally without tenascin. Genes Dev. 6: 1821-1831, 1992. 2. Gulcher, J. R.; Alexakos, M. J.; Le Beau, M. M.; Lemons, R. S.; Stefansson, K. :Chromosomal localization of the human hexabrachion (tenascin) gene and evidence for recent reduplication within the gene. Genomics 6: 616-622, 1990. 3. Gulcher, J. R.; Nies, D. E.; Alexakos, M. J.; Ravikant, N. A.; Sturgill, M. E.; Marton, L. S.; Stefansson, K. : Structure of the human hexabrachion (tenascin) gene. Proc. Nat. Acad. Sci. 88: 9438-9442, 1991. |
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Gene Symbol | TNC |
Alias Symbols | GP, JI, TN, HXB, GMEM, TN-C, DFNA56, 150-225 |
NCBI Gene Id | 3371 |
Protein Name | Tenascin |
Description of Target | The tenascins are a family of extracellular matrix proteins (ECMs). Tenascin is an extracellular matrix protein. It expressed in an unusually restricted pattern during embryogenesis and has been implicated in a variety of morphogenetic phenomena. Human hexabrachion gene(tenascin) is mapped to chromosome 9, bands q32-q34. The coding region of the hexabrachion gene spans approximately 80 kilobases of DNA and consists of 27 exons separated by 26 introns. |
Uniprot ID | P24821 |
Protein interactions
Name | # of Products |
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CNTN1 | 41 |
EGFR | 647 |
FN1 | 361 |
ITGA5 | 130 |
NCAN | 30 |
PTPRB | 28 |
UBC | 7030 |
Biological pathways
Name | # of Products |
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Cell adhesion | 1115 |
Signal transduction | 939 |
Biological process
Name | # of Products |
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Cell adhesion | 446 |
Mesenchymal-epithelial cell signaling involved in prostate gland development | 1 |
Neuromuscular junction development | 20 |
Peripheral nervous system axon regeneration | 8 |
Positive regulation of cell proliferation | 483 |
Positive regulation of gene expression | 160 |
Prostate gland epithelium morphogenesis | 14 |
Response to wounding | 70 |
Signal transduction | 1058 |
Cellular components
Name | # of Products |
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Basement membrane | 61 |
Extracellular matrix | 124 |
Extracellular region | 1573 |
Extracellular space | 884 |
Interstitial matrix | 6 |
Protein function
Name | # of Products |
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Binding | 1030 |
Receptor binding | 932 |
Syndecan binding | 15 |
- TNC Antibody (OASA03310)Catalog #: OASA03310Clone: T2H5Application: ELISA, IHC-PFormat: Liquid. TRIS buffered salineSize: 200UG
- Anti-Tenascin C Polyclonal Antibody (OAAI00437)Catalog #: OAAI00437Application: ELISA, FC, IHC, IP, WBFormat: Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizerSize: 100UG
- TNC ELISA Kit (Human) : 96 Wells (OKEH01405)Catalog #: OKEH01405Application: ELISA-SandwichKit Range: 78-5000pg/mLSensitivity: 20 pg/mLSize: 96T
- TNC ELISA Kit (Rat) (OKCD00854)Catalog #: OKCD00854Application: ELISA-SandwichKit Range: 0.312-20ng/mLSensitivity: < 0.133 ng/mLSize: 96WELLS
- AvivaBlot Femto ECL Reagent (OKCF00002)Catalog #: OKCF00002Application: WBFormat: LiquidSize: 250 mL