Tween 80 [9005-65-6]
Cat# T13947-100mL
Size : 100mL
Brand : TargetMol
Tween 80
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Tween 80
Catalog No. T13947Cas No. 9005-65-6
Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the solubility of compounds in the aqueous phase.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. Pack Size | |
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100 mL |
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
Description | Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the solubility of compounds in the aqueous phase. |
In vitro | METHODS: S. aureus, L. monocytogenes, and P. fluorescens were treated with Tween 80 (0.1% (v/v) in TSB), and growth curves were documented by measuring optical densities at OD600 every 20 min. RESULTS: Tween 80 increased the growth rate of S. aureus. tween 80 did not affect the growth of L. monocytogenes. the growth rate of the P. fluorescens tween 80 group was initially higher than that of the control group, but then declined again, with the maximum OD significantly lower than that of the control. [1] |
In vivo | METHODS: To study the effect of solvents on locomotor activity in mice, Tween-80/Tween-20 (4%-64% (v/v) in saline) was administered intraperitoneally as a single injection to (BALB/c * DBA/2) F1 mice, and the locomotor activity was monitored for 12 h after the administration. RESULTS: Tween-80 significantly decreased the locomotor activity of mice at a concentration of 32%, while Tween-20 significantly decreased the locomotor activity of mice at a concentration of 16%. [2] METHODS: To detect anti-tumor activity in vivo, ATL (15-30 mg/kg in 5% DMSO + 30% PEG300 + 10% Tween 80 + 55% PBS) was injected intraperitoneally into BALB/c mice harboring human thyroid carcinoma tumor 8505C once daily for nine weeks. RESULTS: ATL inhibited the growth of 8505C cell xenografts in vivo. [3] |
Cas No. | 9005-65-6 |
Storage | store at 4°C |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg,each animal weighs 20 g, and the dosage volume is 100 μL. A total of 10 animals were administered, and the formula you used is 5% DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify.
Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Keywords
Tween 80Polysorbate80inhibitTween-80Polysorbate-80Polysorbate 80Tween80Inhibitor