Von Hippel Lindau ELISA Pair
Cat# GTX500022
Size : 1pair
Brand : GeneTex
Contact local distributor :
Phone : +1 850 650 7790
Application | ELISA, Sandwich ELISA |
|---|---|
Reactivity | Human |
| Package | 1 pair |
Datasheet File View product citations for antibody GTX500022 on CiteAb
PRODUCT
Product Content
GTX101087
Type : Capture Antibody
Host : Rabbit
Conjugation : Unconjugated
Package : 50 μl
GTX89268
Type : Detection Antibody
Host : Goat
Conjugation : Unconjugated
Package : 50 μl
APPLICATION
Application Note
We recommend using the capture antibody at a concentration of 2.5μg/mL and the detection antibody at a concentration of 1.5μg/mL. Optimal dilutions should be determined experimentally by the researcher.
PROPERTIES
Form
Liquid
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
Von Hippel-Lindau Tumor Suppressor , Hrca1 , Rca1 , Vhl1 , Pvhl , Vhl
Background
Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
DATA IMAGES
 | GTX500022 ELISA ImageELISA detection of VHL using GTX101087 for capture at a concentration of 2.5 μg/mL and GTX89268 for detection at a concentration of 1.5 μg/mL. The HRP-conjugated anti-goat IgG antibody (GTX26741) was diluted at 1:20,000-1:200,000 and used to detect the primary antibody. |