Early Efficacy of Clone RMP-14 O of PD-1 antibody inveiled/

A new study demonstrates that ichorbio's RMP1-14 (ICH1132) Clone shows significant early-stage efficacy and a consistent performance profile in tumor growth inhibition studies against Competitor B.

A new study demonstrates that ichorbio's RMP1-14 (ICH1132) clone exhibits significant early-stage efficacy and a consistent performance profile in tumor growth inhibition studies compared to the currently established gold standard RMP1-14 clone.

ICH1132 is ichorbio's low endotoxin rat anti-mouse PD-1 antibody

	Early-Stage Efficacy		Significant tumor growth inhibition observed on days 14, 17, and 19 in our recent study.
	Consistent Performance		Trend towards higher tumor growth inhibition percentages compared to Competitor B.
	Lower Endotoxin Levels		ICH1132 (0.013 EU/mg) vs Competitor B (0.056 EU/mg), potentially beneficial for certain research contexts.
	Similar Safety Profile		Comparable effects on body weight to Competitor B, indicating similar tolerability.

ICH1132 vs Competitor B: Tumor Growth Inhibition Tumor Volume Over Time

Tumor Growth Inhibition (TGI) Over Time

This graph illustrates the change in tumor volume over time for three groups: the control group (Isotype Control), and two treatment groups (ICH1132 and Competitor B). The y-axis shows the tumor volume in cubic millimeters (mm³), while the x-axis represents the number of days since treatment began. Error bars indicate the standard error of the mean (SEM) for each data point.

This graph illustrates the Tumor Growth Inhibition (TGI) percentage for ICH1132 and Competitor B over the course of the study. The y-axis represents the TGI percentage, where higher values indicate greater tumor growth inhibition relative to the control group. The x-axis shows the number of days since treatment began.

Key Benefits:

Potential for clearer results in early-stage tumor growth studies.
Opportunity to explore the impact of lower endotoxin levels.
Supports the 3Rs principle in animal research.

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