General Info
Host: | Mouse |
Applications: | AGG/FC/IF/IHC |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Mouse monoclonal antibody anti-Blood Group A (CD173) is suitable for use in AGG, Flow Cytometry, Immunofluorescence and Immunohistochemistry research applications. |
Clonality: | Monoclonal |
Clone ID: | HE-10 |
Conjugation: | Unconjugated |
Isotype: | IgMk |
Formulation: | PBS with 0.02% Sodium Azide. |
Purification: | Affinity purified from tissue culture. |
Concentration: | Can be provided as 100 µg/mL, 500 µg/mL or 1mg/mL. |
Dilution Range: | Agglutination. Flow cytometry (0, 5–1, 0 µg/million cells in 0, 1 ml). Immunofluorescence (0, 5–1 µg/ml). Immunohistology (formalin-fixed: 1-2 µg/ml for 30 min. at RT; requires boiling tissue sections in 10mM citrate buffer, pH 6, 0, for 10-20 min fo |
Storage Instruction: | Store for up to 1 year at 2-8°C upon receipt. |
Information
Immunogen: | A BALB/c mouse was immunized with a mixture of erythrocytes of blood group A1 and a glycoprotein fraction isolated from the saliva of secretors with blood group A of human origin. Fusion partner: P3-X63-Ag8.653. |
Description
Background | Agglutinates erythrocytes of group A, and is excellent as a tumour marker in patients ofblood group B and 0. It does not agglutinate erythrocytes of group B and 0. Study with specificoligosaccharides showed that the antibody HE-10 reacts with A and H antigens with chain types 3 and4 and it does not react with A disaccharide, A trisaccharide, A type 1, A type 2, ALeb. The antibody HE-10 does not react with normal tissue sections of donors with blood group B and 0 but it reactsspecifically with malignant tissues.Immunogen: Mixture of erythrocytes of group A1 and glycoprotein fraction isolated from saliva ofsecretors with blood group A. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance