Anti-HAND2, ID (HAND2, BHLHA26, DHAND, Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2) Polyclonal Antibody

Referencia 036424-200ul

embalaje : 200ul

Marca : US Biological

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036424 HAND2, ID (HAND2, BHLHA26, DHAND, Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
P61296
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_068808.1
Gene #
HAND2
Shipping Temp
Blue Ice
Storage Temp
-20°C

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.||Applications:|Suitable for use in Western Blot, ELISA||Recommended Dilution:|ELISA: 1:1,000|Western Blot: 1:100-500||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: Not Determined |Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.|Purity: Purified by Protein A affinity chromatography.|Immunogen: HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the Central region of human HAND2.|Specificity: Human||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the Central region of human HAND2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Shen, L., et al. Chin. Med. J. 123(13):1623-1627(2010)|Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :|Voth, H., et al. BMC Mol. Biol. 10, 28 (2009) :|Morikawa, Y., et al. Circ. Res. 103(12):1422-1429(2008)|Han, Z., et al. Development 133(6):1175-1182(2006)