HSP90AA1 antibody - N-terminal region
Referencia ARP30184_P050
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HSP90AA1 Antibody - N-terminal region (ARP30184_P050)
| Datasheets/Manuals | Printable datasheet for anti-HSP90AA1 (ARP30184_P050) antibody |
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| Tested Species Reactivity | Human, Mouse |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Sheep |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Additional Information | IHC Information: Tonsil IHC Information: Colon, myenteric plexus |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human HSP90AA1 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 92%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: HLYKDLQPFILLRLLMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIIN |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-HSP90AA1 (ARP30184_P050) antibody is Catalog # AAP30184 (Previous Catalog # AAPS08910) |
| Sample Type Confirmation | HSP90AA1 is strongly supported by BioGPS gene expression data to be expressed in MCF7 |
| Reference | Onuoha,S.C., (2008) J. Mol. Biol. 379 (4), 732-744 |
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| Gene Symbol | HSP90AA1 |
| Gene Full Name | Heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| Alias Symbols | EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, Hsp103, HSPCAL1, HSPCAL4, HEL-S-65p |
| NCBI Gene Id | 3320 |
| Protein Name | Heat shock protein HSP 90-alpha |
| Description of Target | HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. There are 2 major cytosolic HSP90 proteins, HSP90AA1, an inducible form, and HSP90AB1 (MIM 140572), a constitutive form. Other HSP90 proteins are found in endoplasmic reticulum (HSP90B1; MIM 191175) and mitochondria (TRAP1; MIM 606219). |
| Uniprot ID | P07900 |
| Protein Accession # | NP_001017963 |
| Nucleotide Accession # | NM_001017963 |
| Protein Size (# AA) | 854 |
| Molecular Weight | 98kDa |
| Protein Interactions | AHSA1; STUB1; HUWE1; ISG15; RAF1; PTGDS; PTGDR; SIRT1; CDC37; STIP1; HSF1; HIF1A; NR3C1; UBC; PTGES3; FUS; CDC25C; CDK1; SUMO1; STK36; KEAP1; PSMD10; AURKA; SUMO2; SUMO3; MAP3K11; MDM2; LGALS3BP; CEP57; AURKB; CEP76; VHL; TUBG1; TP53; BRCA1; CEP250; AIP; |
