Human Aconitase 2 (ACO2) activation kit by CRISPRa

Referencia GA100038

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Human Aconitase 2 (ACO2) activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ACO2
Locus ID 50
Components

GA100038G1, Aconitase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100038G2, Aconitase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100038G3, Aconitase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001098
UniProt ID Q99798
Synonyms ACONM; HEL-S-284; ICRD; OCA8; OPA9
Summary The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]
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SKU Description Size
KN404307 ACO2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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