General Info
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.125ng/mL |
| Detection Limit: | 0.312-20ng/mL |
| Short Description: | This ADH7 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
| Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 4.5 hrs |
Information
| Gene Symbol: | ADH7 |
| Gene ID: | 131 |
| Uniprot ID: | ADH7_HUMAN |
| Sample Type: | serum, plasma, tissue homogenates or other biological fluids. |
Description
| Tissue Specificity | Preferentially expressed in stomach. |
| Post Translational Modifications | |
| Function | Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation. |
| Protein Name | All-Trans-Retinol Dehydrogenase Nad(+ Adh7Alcohol Dehydrogenase Class 4 Mu/Sigma ChainAlcohol Dehydrogenase Class Iv Mu/Sigma ChainGastric Alcohol DehydrogenaseOmega-Hydroxydecanoate Dehydrogenase Adh7Retinol Dehydrogenase |
| Database Links | Reactome: R-HSA-71384 |
| Cellular Localisation | Cytoplasm |
| Alternative ELISA Names | All-Trans-Retinol Dehydrogenase Nad(+ Adh7 ELISA kitAlcohol Dehydrogenase Class 4 Mu/Sigma Chain ELISA kitAlcohol Dehydrogenase Class Iv Mu/Sigma Chain ELISA kitGastric Alcohol Dehydrogenase ELISA kitOmega-Hydroxydecanoate Dehydrogenase Adh7 ELISA kitRetinol Dehydrogenase ELISA kitADH7 ELISA kit |
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Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance