Human BACE2 activation kit by CRISPRa
Referencia GA108565
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Human BACE2 activation kit by CRISPRa
SKU
GA108565
BACE2 CRISPRa kit - CRISPR gene activation of human beta-secretase 2
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | BACE2 |
| Locus ID | 25825 |
| Components | GA108565G1, BACE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108565G2, BACE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108565G3, BACE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_012105, NM_138991, NM_138992 |
| UniProt ID | Q9Y5Z0 |
| Synonyms | AEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP |
| Summary | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN404860 | BACE2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.