Human Two pore calcium channel protein 2 (TPCN2) activation kit by CRISPRa
Referencia GA116532
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Human Two pore calcium channel protein 2 (TPCN2) activation kit by CRISPRa
SKU
GA116532
TPCN2 CRISPRa kit - CRISPR gene activation of human two pore segment channel 2
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | TPCN2 |
| Locus ID | 219931 |
| Components | GA116532G1, Two pore calcium channel protein 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116532G2, Two pore calcium channel protein 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116532G3, Two pore calcium channel protein 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_139075 |
| UniProt ID | Q8NHX9 |
| Synonyms | SHEP10; TPC2 |
| Summary | This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009] |
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| KN409023 | TPCN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.