HYP2 Recombinant Protein

Referencia OPCA03129-20UG

embalaje : 20ug

Marca : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for HYP2 Recombinant Protein (Baker's yeast) (OPCA03129) (OPCA03129)
Product Info
Predicted Species ReactivitySaccharomyces cerevisiae
Product FormatLiquid or Lyophilized powder
HostYeast
Additional InformationRelevance: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Essential for polarized growth, a process necessary for G1/S transition. May mediate large range of effects of the polyamine spermidine in the cell.
Reconstitution and Storage-20°C or -80°C
Formulation20 mM Tris-HCl based buffer, pH 8.0
PurityGreater than 90% as determined by SDS-PAGE.
Peptide SequenceSDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD
Protein SequenceSDEEHTFETADAGSSATYPMQCSALRKNGFVVIKSRPCKIVDMSTSKTGKHGHAKVHLVAIDIFTGKKLEDLSPSTHNMEVPVVKRNEYQLLDIDDGFLSLMNMDGDTKDDVKAPEGELGDSLQTAFDEGKDLMVTIISAMGEEAAISFKEAARTD
Storage BufferIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
SourceE.coli
Protein Range2-157 aa
TagN-terminal 6xHis-SUMO-tagged
ReferenceTranslation initiation factor 5A and its hypusine modification are essential for cell viability in the yeast Saccharomyces cerevisiae. Schnier J., Schwelberger H.G., Smit-Mcbride Z., Kang H.A., Hershey J.W.B.Mol. Cell. Biol. 11:3105-3114(1991)
Gene SymbolHYP2
Gene Full Nametranslation elongation factor eIF-5A
Alias SymbolseIF-4D;Hypusine-containing protein HP2;TIF51A;translation elongation factor eIF-5A;YEL034W.
NCBI Gene Id856677
Protein NameEukaryotic translation initiation factor 5A-1
Description of TargetmRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Essential for polarized growth, a process necessary for G1/S transition. May mediate large range of effects of the polyamine spermidine in the cell.
Uniprot IDP23301
Protein Accession #NP_010880.3
Nucleotide Accession #NM_001178849.3
Protein Size (# AA)Recombinant
Molecular Weight33 kDa