IWR-1 [1127442-82-3]
Referencia AOB33702-25
embalaje : 25mg
Marca : AOBIOUS
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Data sheet
Molecular Formula | C25H19N3O3 |
Molecular Weight | 409.4 |
CAS Numbers | 1127442-82-3 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | DMSO |
Purity | 98% by HPLC |
SMILES Code | O=C(NC1=C2N=CC=CC2=CC=C1)C3=CC=C(N(C([C@]4(03)[C@](C5)(03)C=C[C@]5(03)[C@]6403)=O)C6=O)C=C3 |
References | 1) Lu J, et al. Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3825-7. 2) Zhang X, et al. Macrophage migration inhibitory factor promotes proliferation and neuronal differentiation of neural stem/precursor cells through Wnt/β-catenin signal pathway. Int J Biol Sci. 2013 Nov 28;9(10):1108-20. |
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A potent inhibitor of the Wnt response, blocking a cell-