IWR-1 [1127442-82-3]

Referencia AOB33702-25

embalaje : 25mg

Marca : AOBIOUS

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IWR-1

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Data sheet

Molecular FormulaC25H19N3O3
Molecular Weight409.4
CAS Numbers1127442-82-3
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(NC1=C2N=CC=CC2=CC=C1)C3=CC=C(N(C([C@]4(03)[C@](C5)(03)C=C[C@]5(03)[C@]6403)=O)C6=O)C=C3
References1) Lu J, et al. Structure-activity relationship studies of small-molecule inhibitors of Wnt response. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3825-7.

2) Zhang X, et al. Macrophage migration inhibitory factor promotes proliferation and neuronal differentiation of neural stem/precursor cells through Wnt/β-catenin signal pathway. Int J Biol Sci. 2013 Nov 28;9(10):1108-20.

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A potent inhibitor of the Wnt response, blocking a cell-based Wnt/β-catenin pathway reporter response.

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AOB1922-10
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