CD55 Unconjugated
Catalog #
Size
Lymphocytes gated cells stained with purified CD55 (clone F4-29D9) followed by donkey anti-mouse IgG iFluor 488 (red histogram). Lymphocytes gated cells stained with purified mouse IgG1 isotype control followed by donkey anti-mouse IgG iFluor 488 (Blue histogram).
| Conjugation | Unconjugated |
|---|---|
| Antigen | CD55 |
| Clone | F4-29D9 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
The clone F4-29D9 binds with a single chain 70kDa glycoprotein and identified as CD55 (also known as decay accelerating factor, DAF). CD55 is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) protein and inhibits autologous complement cascade activation. CD55 also serves as receptor for CD97, echovirus and Coxsackie B virus. Anticd55 is a useful marker for the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH).
The clone F4-29D9 binds with a single chain 70kDa glycoprotein and identified as CD55 (also known as decay accelerating factor, DAF). CD55 is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) protein and inhibits autologous complement cascade activation. CD55 also serves as receptor for CD97, echovirus and Coxsackie B virus. Anticd55 is a useful marker for the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH).