Mouse Aopep activation kit by CRISPRa

Referencia GA209083

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Mouse Aopep activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Aopep
Locus ID 72061
Components

GA209083G1, Aopep gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA209083G2, Aopep gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA209083G3, Aopep gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001289924, NM_001289926, NM_028079, NR_110520, NR_110521
UniProt ID Q8BXQ6
Synonyms 2300006M17Rik; Aopep; AP-O; ApO; AW742919; mir-23b; mir-24-1; mir-27b
Summary Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart.[UniProtKB/Swiss-Prot Function]
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SKU Description Size
KN500211 2010111I01Rik - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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