Mouse AQP5 (Aquaporin 5) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Aqp5
Gene ID:	11830
Uniprot ID:	AQP5_MOUSE
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity	Detected at the luminal membrane of secretory epithelial cells in hindpaw sweat glands. Detected in acinar cells in salivary glands, in duct cells in lacrimal glands and in lung (at protein level). Detected in lung, parotid, submandibular, sublingual, and lacrimal gland tissues.
Post Translational Modifications
Function	Forms a water-specific channel. Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands.
Protein Name	Aquaporin-5 Aqp-5
Database Links	Reactome: R-MMU-432047
Cellular Localisation	Apical Cell Membrane Multi-Pass Membrane Protein Cell Membrane Cytoplasmic Vesicle Membrane Hypotonicity Increases Location At The Cell Membrane Phosphorylation Decreases Location At The Cell Membrane
Alternative ELISA Names	Aquaporin-5 ELISA kit Aqp-5 ELISA kit Aqp5 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance