Mouse Monoclonal Anti-Desmoplakin 1/2, supernatant [Clone DP447]

Referencia 651155

embalaje : 5mL

Marca : Progen

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anti-Desmoplakin 1/2 mouse monoclonal, DP447, supernatant

Quantity 5 ml
Antibody Type Monoclonal
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Application ICC/IF, IHC, WB
Purification Hybridoma cell culture supernatant
Reactivity Bovine, Chicken, Human, Mouse, Trout, Zebrafish
Storage Short term at 2-8°C; long term storage in aliquots at -20°C; avoid freeze/thaw cycles
Intended use Research use only
Clone DP447
Immunogen Synthetic peptide of human desmoplakin 2 (aa 2115-2132)
Formulation Contains 0.09% sodium azide
UniprotID A0A3Q1MR22 (Bovine),E1BWI0 (Chicken),P15924 (Human),E9Q557 (Mouse)
Synonym Desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
Tested applications Tested dilutions
Immunocytochemistry (ICC)/ Immunofluorescence (IF) Assay dependent
Immunohistochemistry (IHC) - frozen Ready-to-use
Immunohistochemistry (IHC) - paraffin Ready-to-use (microwave treatment recommended)
Western Blot (WB) Assay dependent

The antibody shows distinct punctate membrane staining of different epithelia. Area compositae of the myocardium of higher vertebrates are also positive. The epitope is located in a region highly conserved among species (human, zebrafish).
Polypeptides reacting: Desmoplakin 1 and 2.

Reactivity on cultured cell lines: Several human carcinoma cell lines: MCF-7, A-431, HaCaT, CaCo2; bovine cells: MDBK, BMGE; RTG-2 (rainbow trout).

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