PLA2G2A (His-tagged Fusion Protein) Human Protein

Referencia PA521X

embalaje : 100ug

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PLA2G2A (His-tagged Fusion Protein) Human Protein

Specifications
Product Data
Species Human
Expression Host E. coli
Expression cDNA Clone or AA Sequence
Protein Sequence
MRGSHHHHHH GMASHMNLVN FHRMIKLTTG KEAALSYGFY GCHCGVGGRG SPKDATDRCC VTHDCCYKRL EKRGCGTKFL SYKFSNSGSR ITCAKQDSCR SQLCECDKAA ATCFARNKTT YNKKYQYYSN KHCRGSTPRC
Tag His-tag
Concentration lot specific
Purity >95%
presentation_state Purified
Buffer Presentation State: Purified
State: Lyophilized purified protein
Buffer System: 0.05 M Acetate buffer pH4
Preparation Lyophilized purified protein
Application Western Blot.
Protein Description Total 140 AA. MW: 15.8 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
Note Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell cul
Storage Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C.
Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Reference Data
RefSeq NP_000291
Locus ID 5320
UniProt ID P14555
Cytogenetics 1p36.13
Synonyms PLA2B, PLA2L, RASF-A, NPS-PLA2, Group IIA phospholipase A2, Phospholipase A2 membrane associated
Summary The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
Protein Families Western Blot.
Protein Pathways alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway
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