POU2F3 antibody
Referencia GTX17217-100ug
embalaje : 100ug
Marca : GeneTex
Contact local distributor :
Teléfono : +1 850 650 7790
Host | Rabbit |
|---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | WB, IHC-P, ELISA |
Reactivity | Human, Mouse, Rat |
| Package | 100 μg |
Datasheet File View product citations for antibody GTX17217 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| WB | 1 - 2 μg/mL |
| IHC-P | 5 μg/mL |
| ELISA | Assay dependent |
Not tested in other applications.
Calculated MW
47 kDa. ( Note )
Positive Control
SK-N-SH Cell Lysate(GTX23956)
Product Note
At least two isoforms are known to exist. This antibody will recognize both isoforms. POU2F3 antibody is predicted to not cross-react with other members of the POU domain class 2 family.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
POU2F3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human POU2F3.The immunogen is located within amino acids 370 - 420 of POU2F3.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
RRID
AB_2887556
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
POU class 2 homeobox 3 , Epoc-1 , OCT-11 , OCT11 , OTF-11 , PLA-1 , PLA1 , Skn-1a
Cellular Localization
Nucleus
Background
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Database
DATA IMAGES
| | GTX17217 IHC-P Image IHC-P analysis of rat brain tissue using GTX17217 POU2F3 antibody. |
| | GTX17217 IHC-P Image IHC-P analysis of rat brain tissue using GTX17217 POU2F3 antibody. |
| | GTX17217 WB Image WB analysis of SK-N-SH cell lysate using GTX17217 POU2F3 antibody. |
Application Reference
Kudoh S et al. Histochem Cell Biol 2020; Significance of achaete-scute complex homologue 1 (ASCL1) in pulmonary neuroendocrine carcinomas; RNA sequence analyses using small cell lung cancer cells and Ascl1-induced pulmonary neuroendocrine carcinoma cells.
Application : WB
Reactivity : Human
REVIEW
Application Reference
Kudoh S et al. Histochem Cell Biol 2020; Significance of achaete-scute complex homologue 1 (ASCL1) in pulmonary neuroendocrine carcinomas; RNA sequence analyses using small cell lung cancer cells and Ascl1-induced pulmonary neuroendocrine carcinoma cells.
Application : WB
Reactivity : Human
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