stabilin1 (STAB1) (C-term) Goat Polyclonal Antibody
Referencia AP33007PU-N
embalaje : 100ug
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| Product Data | |
| Application | ELISA, IHC |
|---|---|
| Application | Peptide ELISA: 1/8000 (Detection Limit). Immunohistochemistry on Paraffin Sections: 3-5 µg/ml. In paraffin embedded Human Spleen shows endothelial staining. |
| Reactivity | Bovine, Canine, Human, Porcine |
| Antibody Host | Goat |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence C-DFPDTQRILTVK, from the C Terminus of the protein sequence according to NP_055951.2. |
| Specificity | This antibody recognizes Stabilin-1 at C-term. |
| Buffer | Tris saline, pH~7.3 State: Aff - Purified State: Liquid purfied Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide |
| Concentration | lot specific |
| Purification | Antigen Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
| Stability | Shelf life: one year from despatch. |
| Gene Name | stabilin 1 |
| Database Link | |
| Background | Stabilin-1 is a large transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes (Entrez gene 23166). Cellular localization: Membrane; Single-pass type I membrane protein. |
| Synonyms | Stabilin-1, FEEL1, FEEL-1, CLEVER-1, KIAA0246 |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.