TET-IN-C35 (Phylloflavan)
Referencia AOB11121-50
embalaje : 50mg
Marca : AOBIOUS
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Data sheet
| Molecular Formula | C26H26O10 |
| Molecular Weight | 498.48 |
| CAS Numbers | 98570-83-3 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | TETINC35; TETIN-C35; TET-INC35; Phylloflavan; NSC 607319 |
| IUPAC/Chemical Name | (2R,3S)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychroman-3-yl (S)-5-(3,4-dihydroxyphenyl)-3-hydroxypentanoate |
| InChl Key | FKDRTLFRRHQTGU-TYFWRAIDSA-N |
| InChl Code | InChI=1S/C26H26O10/c27-15(4-1-13-2-5-18(29)21(32)7-13)11-25(34)35-24-12-17-20(31)9-16(28)10-23(17)36-26(24)14-3-6-19(30)22(33)8-14/h2-3,5-10,15,24,26-33H,1,4,11-12H2/t15-,24-,26+/m0/s1 |
| SMILES Code | C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)OC(=O)CC(CCC4=CC(=C(C=C4)O)O)O |
| References | 1) Anup Kumar Singh et al., Selective targeting of TET catalytic domain promotes somatic cell reprogramming, PNAS February 18, 2020 117 (7) 3621-3626 |
More info
First-in-class specific inhibitor of Ten-eleven translocation (TET) catalytic domain, reducing 5hmC marks genomewide and promoting somatic cell reprogramming by inducing the BMP-SMAD-ID downstream pathway