Tropomyosin 2 (TPM2) Rabbit Polyclonal Antibody
Referencia TA322875
embalaje : 100ul
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| Product Data | |
| Application | IHC, WB |
|---|---|
| Application | WB: 1000-5000 WB positive control: Human leiomyosarcoma and mouse testis tissue IHC: 25-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 270-284 amino acids of human tropomyosin 2 (beta) |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 33 kDa |
| Gene Name | tropomyosin 2 (beta) |
| Database Link | |
| Background | This gene encodes beta-tropomyosin; a member of the actin filament binding protein family; and mainly expressed in slow; type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins; and cause cap disease; nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Synonyms | AMCD1; DA1; DA2B; HEL-S-273; NEM4; TMSB |
| Reference Data | |
| Protein Pathways | Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM) |
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