• Product Protocol

Specifications

  • Catalog Number K067-H
  • Assay Type Competitive ELISA
  • Sample Types Cell Lysates, Tissue Extracts, Tissue Culture Media
  • Sensitivity 0.048 pmol/mL
  • Species 2',3'-Cyclic GAMP is identical across species
  • Assay Duration 2.5 Hours
  • Samples/Plate 39 in Duplicate
  • Readout Colorimetric, 450 nm

Images

  • 2',3'-Cyclic GAMP ELISA Kit

    2',3'-Cyclic GAMP ELISA Kit - Typical Standard Curve

Recent Publications

View All 27 Publications

  • A novel small molecule Enpp1 inhibitor improves tumor control following radiation therapy by targeting stromal Enpp1 expression

    Published in 2024
    Species: Mouse |
    Sample: Cell Culture |

    Featured Product

    2′,3′-Cyclic GAMP ELISA Kits

  • A STAT3-STING-IFN axis controls the metastatic spread of small cell lung cancer

    Published in 2024
    Species: Mouse |
    Sample: Cell Culture |

    Featured Product

    2′,3′-Cyclic GAMP ELISA Kits

  • BK Polyomavirus infection of bladder microvascular endothelial cells leads to the activation of the cGAS>
    Published in 2024
    Species: Human |
    Sample: Cell Culture |

    Featured Product

    2′,3′-Cyclic GAMP ELISA Kits

  • Immunomodulatory effects of trastuzumab deruxtecan through the cGAS-STING pathway in gastric cancer cells

    Published in 2024
    Species: Human |
    Sample: Cell Lysate |

    Featured Product

    2′,3′-Cyclic GAMP ELISA Kits

  • Inhibiting the cGAS-STING pathway in myeloid cells effectively improves myocardial healing related to TET2 deficiency-induced DNA damage response

    Published in 2024
    Species: Mouse |
    Sample: Cell Lysate |

    Featured Product

    2′,3′-Cyclic GAMP ELISA Kits

Assay Principle:

The DetectX′,3′-Cyclic GAMP ELISA Kit quantitatively measures 2 hours. Please read the complete kit insert before performing this assay.>Protocol Summary:

  • Pipette standards or diluted samples into the provided transparent microtiter plate, pre-coated with goat anti-rabbit IgG antibody.
  • Add 2 hours. The reaction varies inversely with the 2nm and calculate the 2>Background:

    2-IRF3-dependent production of IFN-β.

    The cGAS-cGAMP-STING pathway is not only crucial in pathogen detection but also influences metabolic dysregulation, autoimmunity, and cancer. Understanding the dynamics of this pathway and its molecular components may lead to new therapeutic strategies in immunology and oncology.

    The DetectX′,3′-Cyclic GAMP ELISA Kit offers sensitive and specific quantification of 2′,3′-cGAMP. This kit is valuable for researchers studying cellular responses to DNA stimuli and the broader implications of 2′,3′-cGAMP signaling in health and disease.

2′,3′-Cyclic GAMP ELISA Kits

1 Plate K067-H1
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5 Plates K067-H5
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Research Areas

  • Cell Signaling
  • Inflammation
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