Anti-Hemoglobin F (Human) pAb
Referencia PM078
embalaje : 100uL
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Please Note: MBL International will be shutting down its operations effective December 31, 2024. Distribution of MBL products in the United States will be transferred to Cosmo Bio US on January 1st while European Distributors will remain unchanged. For any US inquiries regarding orders or support during this transition, reach out to Cosmo Bio: https://www.cosmobiousa.com/. For Non-US inquiries reach out to MBL in Japan: https://www.mblbio.com/.
PM078
Antibody
100 uL
| Target | Hemoglobin F |
|---|---|
| Product Type | Antibody |
| Application | IHC |
| Clonality | Polyclonal |
| Conjugate | Unlabeled |
| Isotype | Affinity Purified Ig |
| Immunogen | KLH conjugated synthetic peptide, CLTSLGDAIKH (corresponding to amino acid residues 69-78 of human hemoglobin, gamma A) |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Formulation | PBS containing 1% BSA and 0.09% NaN3 *Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain. |
| Research Area | Cancer, Immunology |
| Description/Background | Human hemoglobin is consists from heterotetramer of two alpha chains and two non-alpha chains,and each poly peptide chain binds one heme. 3 types of hemoglobin, HbA(α2β2), HbA2(α2δ2) and HbF(α2γ2), presents in normal adults. The synthesis of HemoglobinA(HbA) increases after the birth , whereas Hemoglobin F (HbF) rapidly declines to extremely about 1% or less of the whole by the age of 1 year. HbF-containing cells are minor erythrocytes in normal adults, however, detects in fetus and in patients with aplastic anemia, MDS, hemoglobinopathies, and malignancies affecting the erythropoietic system. |
| Storage Temperature | This antibody solution is stable for one year from the date of purchase when stored at 4°C. |
| Protocols | IHC |
| Source | Purified IgG from rabbit serum |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
PM078
Antibody
100 uL