BMPR1A (NM_004329) Human Untagged Clone
Referencia SC127222
embalaje : 10µg
Contact local distributor :
| Product Data | |
| Target Symbol | BMPR1A |
|---|---|
| Synonyms | 10q23del; ACVRLK3; ALK3; CD292; SKR5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data | Fully Sequenced ORF >OriGene ORF sequence for NM_004329 edited AATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCG TCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTCCGTC CGCGCGCGGCGAAGATCGCACGGCCCGATCGAGGGGCGACCGGGTCGGGGCCGCTGCACG CCAAGGGCGAAGGCCGATTCGGGCCCCACTTCGCCCCGGCGGCTCGCCGCGCCCACCCGC TCCGCGCCGAGGGCTGGAGGATGCGTTCCCTGGGGTCCGGACTTATGAAAATATGCATCA GTTTAATACTGTCTTGGAATTCATGAGATGGAAGCATAGGTCAAAGCTGTTTGGAGAAAA TCAGAAGTACAGTTTTATCTAGCCACATCTTGGAGGAGTCGTAAGAAAGCAGTGGGAGTT GAAGTCATTGTCAAGTGCTTGCGATCTTTTACAAGAAAATCTCACTGAATGATAGTCATT TAAATTGGTGAAGTAGCAAGACCAATTATTAAAGGTGACAGTACACAGGAAACATTACAA TTGAACAATGCCTCAGCTATACATTTACATCAGATTATTGGGAGCCTATTTGTTCATCAT TTCTCGTGTTCAAGGACAGAATCTGGATAGTATGCTTCATGGCACTGGGATGAAATCAGA CTCCGACCAGAAAAAGTCAGAAAATGGAGTAACCTTAGCACCAGAGGATACCTTGCCTTT TTTAAAGTGCTATTGCTCAGGGCACTGTCCAGATGATGCTATTAATAACACATGCATAAC TAATGGACATTGCTTTGCCATCATAGAAGAAGATGACCAGGGAGAAACCACATTAGCTTC AGGGTGTATGAAATATGAAGGATCTGATTTTCAGTGCAAAGATTCTCCAAAAGCCCAGCT ACGCCGGACAATAGAATGTTGTCGGACCAATTTATGTAACCAGTATTTGCAACCCACACT GCCCCCTGTTGTCATAGGTCCGTTTTTTGATGGCAGCATTCGATGGCTGGTTTTGCTCAT TTCTATGGCTGTCTGCATAATTGCTATGATCATCTTCTCCAGCTGCTTTTGTTACAAACA TTATTGCAAGAGCATCTCAAGCAGACGTCGTTACAATCGTGATTTGGAACAGGATGAAGC ATTTATTCCAGTTGGAGAATCACTAAAAGACCTTATTGACCAGTCACAAAGTTCTGGTAG TGGGTCTGGACTACCTTTATTGGTTCAGCGAACTATTGCCAAACAGATTCAGATGGTCCG GCAAGTTGGTAAAGGCCGATATGGAGAAGTATGGATGGGCAAATGGCGTGGCGAAAAAGT GGCGGTGAAAGTATTCTTTACCACTGAAGAAGCCAGCTGGTTTCGAGAAACAGAAATCTA CCAAACTGTGCTAATGCGCCATGAAAACATACTTGGTTTCATAGCGGCAGACATTAAAGG TACAGGTTCCTGGACTCAGCTCTATTTGATTACTGATTACCATGAAAATGGATCTCTCTA TGACTTCCTGAAATGTGCTACACTGGACACCAGAGCCCTGCTTAAATTGGCTTATTCAGC TGCCTGTGGTCTGTGCCACCTGCACACAGAAATTTATGGCACCCAAGGAAAGCCCGCAAT TGCTCATCGAGACCTAAAGAGCAAAAACATCCTCATCAAGAAAAATGGGAGTTGCTGCAT TGCTGACCTGGGCCTTGCTGTTAAATTCAACAGTGACACAAATGAAGTTGATGTGCCCTT GAATACCAGGGTGGGCACCAAACGCTACATGGCTCCCGAAGTGCTGGACGAAAGCCTGAA CAAAAACCACTTCCAGCCCTACATCATGGCTGACATCTACAGCTTCGGCCTAATCATTTG GGAGATGGCTCGTCGTTGTATCACAGGAGGGATCGTGGAAGAATACCAATTGCCATATTA CAACATGGTACCGAGTGATCCGTCATACGAAGATATGCGTGAGGTTGTGTGTGTCAAACG TTTGCGGCCAATTGTGTCTAATCGGTGGAACAGTGATGAATGTCTACGAGCAGTTTTGAA GCTAATGTCAGAATGCTGGGCCCACAATCCAGCCTCCAGACTCACAGCATTGAGAATTAA GAAGACGCTTGCCAAGATGGTTGAATCCCAAGATGTAAAAATCTGATGGTTAAACCATCG GAGGAGAAACTCTAGACTGCAAGAACTGTTTTTACCCATGGCATGGGTGGAATTAGAGTG GAATAAGGATGTTAACTTGGTTCTCAGACTCTTTCTTCACTACGTGTTCACAGGCTGCTA ATATTAAACCTTTCAGTACTCTTATTAGGATACAAGCTGGGAACTTCTAAACACTTCATT CTTTATATATGGACAGCTTTATTTTAAATGTGGTTTTTGATGCCTTTTTTTAAGTGGGTT TTTATGAACTGCATCAAGACTTCAATCCTGATTAGTGTCTCCAGTCAAGCTCTGGGTACT GAATTGCCTGTTCATAAAACGGTGCTTTCTGTGAAAGCCTTAAGAAGATAAATGAGCGCA GCAGAGATGGAGAAATAGACTTTGCCTTTTACCTGAGACATTCAGTTCGTTTGTATTCTA CCTTTGTAAAACAGCCTATAGATGATGATGTGTTTGGGATACTGCTTATTTTATGATAGT TTGTCCTGTGTCCTTAGTGATGTGTGTGTGTCTCCATGCACATGCACGCCGGGATTCCTC TGCTGCCATTTGAATTAGAAGAAAATAATTTATATGCATGCACAGGAAGATATTGGTGGC CGGTGGTTTTGTGCTTTAAAAATGCAATATCTGACCAAGATTCGCCAATCTCATACAAGC CATTTACTTTGCAAGTGAGATAGCTTCCCCACCAGCTTTATTTTTTAACATGAAAGCTGA TGCCAAGGCCAAAAGAAGTTTAAAGCATCTGTAAATTTGGACTGTTTTCCTTCAACCACC ATTTTTTTTGTGGTTATTATTTTTGTCACGGAAAGCATCCTCTCCAAAGTTGGAGCTTCT ATTGCCATGAACCATGCTTACAAAGAAAGCACTTCTTATTGAAGTGAATTCCTGCATTTG ATAGCAATGTAAGTGCCTATAACCATGTTCTATATTCTTTATTCTCAGTAACTTTTAAAA GGGAAGTTATTTATATTTTGTGTATAATGTGCTTTATTTGCAAATCACCCACTCCTTTAC AACCATACTTTATATATGTACATACATTCATACTGTAGAAACCAGCTCATGTGTACCTCA TATCCCATCCTTAAGAGAAGAAATGTTATAAAGTAGAACTAAATATAAATTTTCAGAATT AATGCATTCAAAGTAATATATCAAATCCAGGACTTTGTTAACTTCAGGTAAAAACTTCAT TAGGGTAATATCATCTCAATTTTTTCAAATGAAAGGATTCTCTAATTAGAAATTTATATG TCAGAGCTGTTATAAATTTATCAACTGTCAAATATGTTCTGGACAGCTAAATCATTTGAG ATTTTTGGTTTTTTGATTTCTATTCCCTAACTTGTGAAGACAATGAAAAATCAGGCAGAA ATATTTAGTATCTAGTCAGTATCTGTAGCTACACTGTATAACTGTTCTTCAATAAAATGG TTCATATTTTATAGAAAAAAAAAAAAAAAAAAAAAA 5' Read Nucleotide Sequence >OriGene 5' read for NM_004329 unedited TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGTCCGTCCGCGCGCGG CGAAGATCGCACGGCCCGATCGAGGGGCGACCGGGTCGGGGCCGCTGCACGCCAAGGGCG AAGGCCGATTCGGGCCCCACTTCGCCCCGGCGGCTCGCCGCGCCCACCCGCTCCGCGCCG AGGGCTGGAGGATGCGTTCCCTGGGGTCCGGACTTATGAAAATATGCATCAGTTTAATAC TGTCTTGGAATTCATGAGATGGAAGCATAGGTCAAAGCTGTTTGGAGAAAATCAGAAGTA CAGTTTTATCTAGCCACATCTTGGAGGAGTCGTAAGAAAGCAGTGGGAGTTGAAGTCATT GTCAAGTGCTTGCGATCTTTTACAAGAAAATCTCACTGAATGATAGTCATTTAAATTGGT GAAGTAGCAAGACCAATTATTAAAGGTGACAGTACACAGGAAACATTACAATTGAACAAT GCCTCAGCTATACATTTACATCAGATTATTGGGAGCCTATTTGTTCATCATTTCTCGTGT TCAAGGACAGAATCTGGATAGTATGCTTCATGGCACTGGGATGAAATCAGACTCCGACCA GAAAAAGTCAGAAAATGGAGTAACCTTAGCACCAGAGGATACCTTGCCTTTTTTAAAGTG CTATTGCTCAGGGCACTGTCCAGATGATGCTATTAATAACACATGCATAACTAATGGACA TTGCTTTGCCATCATAGAAGAAGATGACCAGGGAGAAACCACATTAGCTTCAGGGTGTAT GAAATATGAAGGATCTGATTTTCAGTGCAAAGATTCTNCANAAGCCCAGCTACGCCCGGA CATAGAATGTTGTCGGACCAATTTATGTNACCAGTATTTGCAACCACACTNNGCCCCTGT GTCAATAGGTCCCGTTTTTGATGCAGCATCGAATGGCTGGTC 3' Read Nucleotide Sequence >OriGene 3' read for NM_004329 unedited GCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTCTATAAAATATGAACCATT TTATTGAAGAACAGTTATACAGTGTAGCTACAGATACTGACTAGATACTAAATATTTCTG CCTGATTTTTCATTGTCTTCACAAGTTAGGGAATAGAAATCAAAAAACCAAAAATCTCAA ATGATTTAGCTGTCCAGAACATATTTGACAGTTGATAAATTTATAACAGCTCTGACATAT AAATTTCTAATTAGAGAATCCTTTCATTTGAAAAAATTGAGATGATATTACCCTAATGAA GTTTTTACCTGAAGTTAACAAAGTCCTGGATTTGATATATTACTTTGAATGCATTAATTC TGAAAATTTATATTTAGTTCTACTTTATAACATTTCTTCTCTTAAGGATGGGATATGAGG TACACATGAGCTGGTTTCTACAGTATGAATGTATGTACATATATAAAGTATGGTTGTAAA GGAGTGGGTGATTTGCAAATAAAGCACATTATACACAAAATATAAATAACCTTCCCTTTT AAAAGTTACTGAGAATAAAGAATATAGAACATGGTTATAGGCACTTACATTGCTATCAAA TGCAGGAATTCACTTCAATAAGAGTGCTTTCTTTGTAGCATGTTCATGGCATAGAAGCTC ACTTTGGAGAGATGCTTTCGTGACAAAAATATACCACAAAAAAATGTGGGTTGAGGAAAC AGNTCAAATTACAGATGCTTTAAACTTCTTTGGGNCTTGGCATCAGCTTTCATGGTAAAA ATAAAGCTGGTGGGGAAGCTATCTACTTGCAAGTAAATGGCTTGATGAAATTGCGAATCT TGTCAGATTTGCATTTTTAAGCACAAACCCCGGCACCAATATTNCGTGGCAGCATATAAT TTTTTCTCTATTCAATGCAACAAGAATCCCGGTGCTTTGCCTGGGACCCCCCCTTCCTAG CCCCGACAAACTTCTAAATAGNCGTTCCCACCCATATCTTTAGCCGGTTCAAGGTAAATC ACAACTGAG |
| Restriction Sites | NotI-NotI Plasmid Map  |
| ACCN | NM_004329 |
| Insert Size | 3370 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20um filter is required. |
| Reference Data | |
| RefSeq | NM_004329.2, NP_004320.2 |
| RefSeq Size | 3631 bp |
| RefSeq ORF | 1599 bp |
| Locus ID | 657 |
| UniProt ID | P36894 |
| Cytogenetics | 10q23.2 |
| Domains | Activin_recp, GS, pkinase, S_TKc, TyrKc |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Protein Kinase, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway |
| Summary | The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq, Jul 2008] |
| SKU | Description | Size | ||
|---|---|---|---|---|
| RC206048 | BMPR1A (Myc-DDK-tagged)-Human bone morphogenetic protein receptor, type IA (BMPR1A) | 10 ug | | |
| RC206048L1 | Lenti ORF clone of Human bone morphogenetic protein receptor, type IA (BMPR1A), Myc-DDK-tagged | 10 ug | | |
| RC206048L2 | Lenti ORF clone of Human bone morphogenetic protein receptor, type IA (BMPR1A), mGFP tagged | 10 ug | | |
| RC206048L3 | Lenti ORF clone of Human bone morphogenetic protein receptor, type IA (BMPR1A), Myc-DDK-tagged | 10 ug | | |
| RC206048L4 | Lenti ORF clone of Human bone morphogenetic protein receptor, type IA (BMPR1A), mGFP tagged | 10 ug | | |
| RG206048 | BMPR1A (tGFP-tagged) - Human bone morphogenetic protein receptor, type IA (BMPR1A) | 10 ug | MSRP MSRP | |
| SC323635 | BMPR1A (untagged)-Kinase deficient mutant (K261M) of Human bone morphogenetic protein receptor, type IA (BMPR1A) | 10 ug | | |