Human Inosine triphosphate pyrophosphatase (ITPA) activation kit by CRISPRa
Referencia GA102492
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Human Inosine triphosphate pyrophosphatase (ITPA) activation kit by CRISPRa
SKU
GA102492
ITPA CRISPRa kit - CRISPR gene activation of human inosine triphosphatase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | ITPA |
| Locus ID | 3704 |
| Components | GA102492G1, Inosine triphosphate pyrophosphatase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102492G2, Inosine triphosphate pyrophosphatase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102492G3, Inosine triphosphate pyrophosphatase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001267623, NM_033453, NM_181493, NR_052000, NR_052001, NR_052002, NM_001324236, NM_001324237, NM_001324238, NM_001324240, NM_001351739 |
| UniProt ID | Q9BY32 |
| Synonyms | C20orf37; dJ794I6.3; HLC14-06-P; My049 |
| Summary | This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN404021 | ITPA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.