CD71 Unconjugated
Catalog #
Size
Live Jurkat gated cells stained with purified CD71 (clone OKT9) followed by donkey anti-mouse IgG iFluor 488 (red histogram). Live Jurkat gated cells stained with purified mouse IgG1 isotype control followed by donkey anti-mouse IgG iFluor 488 (Blue histogram).
| Conjugation | Unconjugated |
|---|---|
| Antigen | CD71 |
| Clone | OKT9 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
Description:
The antibody is directed against the transferrin receptor (CD71), the 95 kDa, type II membrane glycoprotein. CD71 is expressed on activated, but not resting lymphocytes, monocytes, macrophages, most dividing cells and on brain endothelium, and is upregulated during response to antigens and/or mitogens. The transferrin receptor binds Fe(Apo)-transferrin and via endocytosis and delivers iron required by the growing cell for cellular metabolism.
The antibody is directed against the transferrin receptor (CD71), the 95 kDa, type II membrane glycoprotein. CD71 is expressed on activated, but not resting lymphocytes, monocytes, macrophages, most dividing cells and on brain endothelium, and is upregulated during response to antigens and/or mitogens. The transferrin receptor binds Fe(Apo)-transferrin and via endocytosis and delivers iron required by the growing cell for cellular metabolism.