RC223878L1 | P2Y2 (P2RY2) (NM_176071) Human Tagged Lenti ORF Clone

Specifications

Specifications
Product Data
Target Symbol	P2Y2
Synonyms	HP2U; P2RU1; P2U; P2U1; P2UR; P2Y2; P2Y2R
Vector	pLenti-C-Myc-DDK
E. coli Selection	Chl (34 ug/mL)
Mammalian Cell Selection	None
Sequence Data	ORF Nucleotide Sequence The ORF insert of this clone is exactly the same as(RC223878).
Restriction Sites	SgfI-MluI Cloning Scheme for this gene Plasmid Map
ACCN	NM_176071
ORF Size	1131 bp
OTI Disclaimer	The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20um filter is required.
Reference Data
RefSeq	NM_176071.1
RefSeq Size	2613 bp
RefSeq ORF	1134 bp
Locus ID	5029
UniProt ID	P41231
Cytogenetics	11q13.4
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction
MW	42.1 kDa
Summary	The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]

Documents

Resources

"NM_176071" in other vectors (6)

SKU	Description	Size
RC223878	P2RY2 (Myc-DDK-tagged)-Human purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 3	10 ug
RC223878L2	Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 3, mGFP tagged	10 ug
RC223878L3	Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 3, Myc-DDK-tagged	10 ug
RC223878L4	Lenti ORF clone of Human purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 3, mGFP tagged	10 ug
RG223878	P2RY2 (tGFP-tagged) - Human purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 3	10 ug
SC309531	P2RY2 (untagged)-Human purinergic receptor P2Y, G-protein coupled, 2 (P2RY2), transcript variant 3	10 ug