Stemolecule™ ec23
SRP002 / SRP002-2
Brand: Stemolecule
A light-stable pan-RAR receptor agonist that maintains the same biological activity as ATRA (all-trans retinoic acid).
CAS Number: 104561-41-3
Alternate Name(s):
- 4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-ylethynyl) benzoic acid
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Product Information
Human TERA2.cl.SP12 EC cells exposed to either ec23 or ATRA form populations of terminally differentiated neurons after 21 days. Immunocytochemical staining for neurofilament-200 was performed on differentiated cultures.
SR-P002 and SR-P002-2 SDS
Christie VB; Barnard JH; Batsanov AS; Bridgens CE; Cartmell EB; Collings JC; Maltman DJ; Redfern CPF; Marder TB; Przyborski S; Whiting A. Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org Biomol Chem 6: 3497 (2008).
Additional Publications
- Goncalves KE; Phillips S; Shah DSH; Athey D; Przyborski S. Application of biomimetic surfaces and 3D culture technology to study the role of extracellular matrix interactions in neurite outgrowth and inhibition. Biomaterials Advances 144:213204 (2022).
- Tan SM; Altschuler G; Zhao TY; Ang HS; Yang H; Lim B; Vardy L; Hide W; Thomson AM; Lareu RR. Divergent LIN28-mRNA associations result in translational suppression upon the initiation of differentiation. Nucl Acids Res 42: 7997 (2014).
- Clemens G; Flower KR; Henderson AP; Whiting A; Przyborski SA; Jimenez-Hernandez M; Ball F; Basssan P; Cinque G; Gardner P. The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Mol Biol Syst 9: 699 (2013).