Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:MEM-111)-PE Conjugated

Imprimir

Referência 30-2176-100

Tamanho : 100Testss

Contactar o distribuidor local :

Telefone : +1 850 650 7790

Marca : Abeomics

Solicitar mais informações

Contactar o distribuidor local :

Telefone : +1 850 650 7790

Anti-CD54 / ICAM-1 Monoclonal Antibody (Clone:MEM-111)-PE Conjugated

Figure 1: Western blottin analysis of CD54 expression in TNF-alpha activated (A) and nonactivated (B) HUVEC cells by antibody MEM-111. Lower bands represent tubulin as a loading control.

Amount :	100 tests
Isotype :	Mouse IgG2a
Storage condition :	Store in the dark at 2-8px ! important;width:210px">
Gene :	ICAM1
Gene ID :	3383
Uniprot ID :	P05362
Alternative Name :	ICAM1
Immunogen Information :	Raji human Burkitt's lymphoma cell line

CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation.

Subcellular location:	Membrane
Post transnational modification:	Monoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
BioGrid:	109610. 178 interactions.

There are currently no product reviews

Write a review on this product!