BIRC5 (phospho S20) polyclonal antibody (DyLight 550)

Catalog # PAB15180

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Size:100 uL
Price: USD $ 638.00
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Contact Info
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  • Specifications

    Product Description

    Rabbit polyclonal antibody raised against synthetic phosphopeptide of BIRC5.

    Immunogen

    Synthetic phosphopeptide corresponding to residues surrounding S20 of human BIRC5.

    Host

    Rabbit

    Reactivity

    Human

    Specificity

    This antibody is useful for Western blot, where a band is seen ~16.5 KDa.

    Form

    Liquid

    Conjugation

    DyLight 550

    Purification

    Immunogen affinity purification

    Recommend Usage

    Western Blot (3 ug/mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 50 mM sodium borate (0.05% sodium azide).

    Storage Instruction

    Store at 4°C in the dark.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

  • Gene Info — BIRC5

    Entrez GeneID

    332

    Protein Accession#

    O15392

    Gene Name

    BIRC5

    Gene Alias

    API4, EPR-1

    Gene Description

    baculoviral IAP repeat-containing 5

    Omim ID

    603352

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq

    Other Designations

    apoptosis inhibitor 4|baculoviral IAP repeat-containing protein 5|survivin variant 3 alpha

  • Interactomes
  • Pathways
  • Diseases