CLK4 antibody - N-terminal region
Referência ARP30645_P050
Tamanho : 100ul
Marca : Aviva Systems Biology
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CLK4 Antibody - N-terminal region (ARP30645_P050)
| Datasheets/Manuals | Printable datasheet for anti-CLK4 (ARP30645_P050) antibody |
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| Publications | Eisenreich, A. et al. Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells. Oncol. Rep. 30, 462-70 (2013). 23604472 |
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| Tested Species Reactivity | Human |
| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Yeast: 91% |
| Peptide Sequence | Synthetic peptide located within the following region: RSRRSSPKRKRNRHCSSHQSRSKSHRRKRSRSIEDDEEGHLICQSGDVLR |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-CLK4 (ARP30645_P050) antibody is Catalog # AAP30645 (Previous Catalog # AAPP01302) |
| Gene Symbol | CLK4 |
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| Gene Full Name | CDC-like kinase 4 |
| Alias Symbols | DKFZp686A20267 |
| NCBI Gene Id | 57396 |
| Protein Name | Dual specificity protein kinase CLK4 |
| Description of Target | The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined. |
| Uniprot ID | Q9HAZ1 |
| Protein Accession # | NP_065717 |
| Nucleotide Accession # | NM_020666 |
| Protein Size (# AA) | 481 |
| Molecular Weight | 57 |
| Protein Interactions | KPNA1; KRTAP10-3; KRTAP10-8; KRTAP10-9; KRTAP10-7; CLK4; SRRM2; AHCYL2; SUB1; RASA4; SRPK1; RNF181; CLASRP; UBL5; HSPB2; |
