FGG Recombinant Protein
Referência OPCD08077-50UG
Tamanho : 50ug
Marca : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for FGG Recombinant Protein (OPCD08077) |
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| Predicted Species Reactivity | Homo sapiens|Human |
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| Product Format | Freeze-dried Powder. PBS, pH7.4, containing 5% Trehalose. |
| Host | Yeast |
| Conjugation | Unconjugated |
| Application | Ctrl (+), SDS-PAGE, WB |
| Additional Information | Endotoxin Level: < 1.0 EU per 1 ug (determined by the LAL method) |
| :: | Residues: Lys166-Asn416 |
| :: | Subcellular Location: Secreted |
| Reconstitution and Storage | 2°C to 8°C|-80°C |
| Concentration | 200 ug/mL (prior to lyoph) |
| Purity | > 95% |
| Source | Yeast |
| Tag | N-terminal His Tag |
| Gene Symbol | FGG |
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| Gene Full Name | fibrinogen gamma chain |
| Alias Symbols | fibrinogen gamma chain;fibrinogen, gamma polypeptide;testicular tissue protein Li 70. |
| NCBI Gene Id | 2266 |
| Protein Name | Fibrinogen gamma chain |
| Description of Target | Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways. |
| Uniprot ID | P02679 |
| Protein Accession # | NP_000500.2 |
| Nucleotide Accession # | NM_000509.5 |
| Protein Size (# AA) | Lys166~Asn416 |
| Molecular Weight | 30kDa |