Human SIRT5 activation kit by CRISPRa
Referência GA108286
Tamanho : 1kit
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Human SIRT5 activation kit by CRISPRa
SKU
GA108286
SIRT5 CRISPRa kit - CRISPR gene activation of human sirtuin 5
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | SIRT5 |
| Locus ID | 23408 |
| Components | GA108286G1, SIRT5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA108286G2, SIRT5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA108286G3, SIRT5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001193267, NM_001242827, NM_012241, NM_031244 |
| UniProt ID | Q9NXA8 |
| Synonyms | SIR2L5 |
| Summary | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN400189 | SIRT5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.