Human UDP glucose dehydrogenase (UGDH) activation kit by CRISPRa
Referência GA105069
Tamanho : 1kit
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Human UDP glucose dehydrogenase (UGDH) activation kit by CRISPRa
SKU
GA105069
UGDH CRISPRa kit - CRISPR gene activation of human UDP-glucose 6-dehydrogenase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | UGDH |
| Locus ID | 7358 |
| Components | GA105069G1, UDP glucose dehydrogenase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105069G2, UDP glucose dehydrogenase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105069G3, UDP glucose dehydrogenase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_001184700, NM_001184701, NM_003359 |
| UniProt ID | O60701 |
| Synonyms | GDH; UDP-GlcDH; UDPGDH; UGD |
| Summary | The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010] |
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| SDS |
| SKU | Description | Size | ||
|---|---|---|---|---|
| KN402132 | UGDH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.