CD10 APC
Catalog #
Size
Live Reh gated cells stained with CD10 (C-1A12) APC (RED); Live Reh are used as FMO control (BLUE).
| Conjugation | APC |
|---|---|
| Antigen | CD10 |
| Clone | C-1A12 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
| Excitation Laser | Red (633nm) |
Description:
The clone C-1A12, a mouse monoclonal antibody recognizes a 100 kDa protein that has neutral metalloendopeptidase activity and inactivates a variety of biologically active peptides known as CD10. CD10 is type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. CD10 plays important role in the development process of B cells the in germinal center. This protein is not restricted to leukemic cells. Normal, healthy precursors of B and T cells and granulocytes also express CD10.
The clone C-1A12, a mouse monoclonal antibody recognizes a 100 kDa protein that has neutral metalloendopeptidase activity and inactivates a variety of biologically active peptides known as CD10. CD10 is type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. CD10 plays important role in the development process of B cells the in germinal center. This protein is not restricted to leukemic cells. Normal, healthy precursors of B and T cells and granulocytes also express CD10.