CD14 FITC
Catalog #
Size
Monocytes gated PBMCs stained with CD14 (C-2386) FITC (RED); Monocytes gated PBMCs are used as FMO control (BLUE).
| Conjugation | FITC |
|---|---|
| Antigen | CD14 |
| Clone | C-2386 |
| Isotype | IgG1, k |
| Applications | FC |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Primary/Secondary | Primary |
| Storage | 2-8°C |
| Status | RUO |
| Excitation Laser | Blue (488nm) |
| Immunogen | Recombinant fragment of human CD14 protein (around aa 25-148) |
Description:
The clone C-2386, a mouse monoclonal antibody reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. C-2386 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.
The clone C-2386, a mouse monoclonal antibody reacts with a human 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain cell surface antigen known as CD14. The CD14 expression is commonly observed on monocytes, interfollicular macrophages, reticular dendritic cells and some Langerhans cells. C-2386 binds with a complex of LPS and lipopolysaccharide binding protein, and blockade of CD14 with monoclonal antibodies prevented the synthesis of TNF-alpha by LPS activated leukocytes.