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Western Blot (Cell lysate)
Application

Western Blot (Cell lysate)

Western blot analysis of 293T cell lysate with MRC1 monoclonal antibody.

  • Specifications

    Product Description

    Rabbit monoclonal antibody raised against synthetic peptide of human MRC1.

    Immunogen

    A synthetic peptide corresponding to human MRC1.

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Purification

    Affinity purification

    Isotype

    IgG

    Recommend Usage

    Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

    Storage Instruction

    Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot (Cell lysate)

    Western blot analysis of 293T cell lysate with MRC1 monoclonal antibody.

    Immunocytochemistry

    Immunofluorescence

  • Gene Info — MRC1

    Entrez GeneID

    4360

    Protein Accession#

    P22897

    Gene Name

    MRC1

    Gene Alias

    CD206, CLEC13D, MMR

    Gene Description

    mannose receptor, C type 1

    Omim ID

    153618

    Gene Ontology

    Hyperlink

    Gene Summary

    The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq

    Other Designations

    OTTHUMP00000019245|OTTHUMP00000045206|macrophage mannose receptor|mannose receptor C type 1

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  • Diseases