OGG1 Protein
Referência OPPA02473
Tamanho : 5ug
Marca : Aviva Systems Biology
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| Datasheets/Manuals | Printable datasheet for OPPA02473 |
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| Predicted Species Reactivity | Human |
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| Product Format | 0.5mg/ml solution containing 20mM Tris buffer pH-8, 0.1M NaCl and 40% Glycerol. Physical appearance: Sterile filtered colorless solution. |
| Host | E. Coli |
| :: | Product Introduction: OGG1 is a DNA glycosylase enzyme which takes part in base excision repair. OGG1 protein is the main enzyme accountable for the excision of 7,8-dihydro-8-oxoguanine (8-oxoG), a mutagenic base byproduct which arises as a result of exposure to reactive oxygen species (ROS). OGG1 shows beta lyase activity that nicks DNA 3'' to the lesion. Product Description: OGG1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345 a.a.) and having a molecular mass of 41.2 kDa. The OGG1 is fused to 23 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
| Reconstitution and Storage | OGG1 Human although stable at 4C for 1 week, should be stored below -18C. Please prevent freeze thaw cycles. |
| Purity | Greater than 90.0% as determined by SDS-PAGE. |
| Peptide Sequence | MGSSHHHHHH SSGLVPRGSH TGSMPARALL PRRMGHRTLA STPALWASIP CPRSELRLDL VLPSGQSFRW REQSPAHWSG VLADQVWTLTQTEEQLHCTV YRGDKSQASR PTPDELEAVR KYFQLDVTLA QLYHHWGSVD SHFQEVAQKF QGVRLLRQDP IECLFSFICS SNNNIARITGMVERLCQAFG PRLIQLDDVT YHGFPSLQAL AGPEVEAHLR KLGLGYRARY VSASARAILE EQGGLAWLQQ LRESSYEEAH KALCILPGVGTKVADCICLM ALDKPQAVPV DVHMWHIAQRDYSWHPTTSQ AKGPSPQTNK ELGNFFRSLW GPYAGWAQAV LFSADLRQCR HAQEPPAKRR.KGSKGPEG |
| Gene Symbol | OGG1 |
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| Alias Symbols | HMMH, MUTM, OGH1, HOGG1 |
| NCBI Gene Id | 4968 |
| Protein Name | N-glycosylase/DNA lyase |
| Description of Target | Recombinant Human 8-Oxoguanine DNA Glycosylase |
| Uniprot ID | O15527 |
| Protein Accession # | NP_002533.1 |
| Protein Size (# AA) | Recombinant |