Protein analytics
We offer a range of analytical methods utilizing multiple assay platforms that be used to characterize a broad range of proteins expressed and purified by various methods.
Our team will work closely with you from concept through delivery. Together, we'll develop a set of project deliverables tailored to your specifications of scale, purity, activity and other analytical characteristics on a timeline that meets your needs.
You will find below the various services that we offer. Please contact us at tech@quimigen.pt for more information or for a quote request.
Protein activity
- Binding affinity (FortéBio Octet® RED96 System)
- Enzyme activity
- Cell-based assays
- In vivo testing
Aggregation status
- SDS-PAGE
- SEC-HPLC
- Optical density
Protein stability
- Tm&Tagg
- ΔG
- Isothermal stability
- Thermal recovery
- Sizing&polydispersity
- Sizing with thermal ramp
- B22&kD
- Viscosity
Protein integrity and structure
- SEC-HPLC
- SDS-PAGE
- N-glycan analysis
- Western Blot
Protein mass (Agilent HPLC-CHIP/QTOF)
- Accurate mass: proteins, protein-drug conjugates
- Peptide and Glycan mapping
- Determination of post-translations modifications either in known or unknown samples.
- Standard COAs